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The classic textbook on mechanistic organic chemistry, characterised particularly by its clarity, careful choice of examples, and its general approach that is designed to lead to a ready understanding of the subject matter. The book is aimed clearly at the needs of the student, with a thorough understanding of, and provision for, the potential conceptual difficulties he or she is likely to encounter.
Featuring new experiments unique to this lab textbook, as well as new and revised essays and updated techniques, this Sixth Edition provides the up-to-date coverage students need to succeed in their coursework and future careers. From biofuels, green chemistry, and nanotechnology, the book’s experiments, designed to utilize microscale glassware and equipment, demonstrate the relationship between organic chemistry and everyday life, with project-and biological or health science focused experiments. As they move through the book, students will experience traditional organic reactions and syntheses, the isolation of natural products, and molecular modeling.
About the Author
Randall G. Engel has taught chemistry for almost 35 years. He has co-authored with Donald Pavia, Gary Lampman, and George Kriz INTRODUCTION TO ORGANIC LABORATORY TECHNIQUES: A MICROSCALE APPROACH (Cengage Learning), and A SMALL SCALE INTRODUCTION TO ORGANIC LABORATORY TECHNIQUES (Cengage Learning). Their book, MICROSCALE AND MACROSCALE TECHNIQUES IN THE ORGANIC LABORATORY (Cengage Learning), includes techniques only, and can be used with a faculty member’s own experiments. Engel received his B.A. degree in chemistry from Cornell College and his M.S. degree in chemistry from Western Washington University. He began his teaching career at Wenatchee Valley College in 1975 and continued at Green River Community College and Edmonds Community College. Presently he teaches organic chemistry on a part-time basis at North Seattle Community College. Donald L. Pavia earned his BS degree in chemistry from Reed College and his PhD in organic chemistry from Yale University. In 1970, he joined the faculty at Western Washington University as Assistant Professor and now holds the rank of Professor Emeritus. He is the coauthor of two organic laboratory books that include techniques and experiments: INTRODUCTION TO ORGANIC LABORATORY TECHNIQUES: A MICROSCALE APPROACH (Cengage Learning), and A SMALL SCALE APPROACH TO ORGANIC LABORATORY TECHNIQUES (Cengage Learning), as well as MICROSCALE AND MACROSCALE TECHNIQUES IN THE ORGANIC LABORATORY (Cengage Learning), which highlights techniques to be used with a faculty member’s own experiments. He is a co-author, with Gary M. Lampman, George S. Kriz and James R. Vyvyan of an organic spectroscopy book, INTRODUCTION TO SPECTROSCOPY (Cengage Learning). Professor Pavia’s research interests center on the synthesis and reactions of valence tautomeric and photochromic compounds, especially pyrylium-3-oxide tautomers. Autoxidations are a special interest. His other interests include the use of computers in teaching organic chemistry, both for lecture presentation and for the simulation of laboratories. He is the author of several computer programs. One such program is SQUALOR (Simulated Qualitative Organic Analysis) for which he won the 1986 EDUCOM/NCRIPTAL award. The program is designed for teaching the methods for solving organic unknowns. Gary M. Lampman earned his BS degree in chemistry from the University of California, Los Angeles, and his PhD in organic chemistry from the University of Washington. In 1964, he joined the faculty at Western Washington University as Assistant Professor, rising to Professor in 1973. He received the Outstanding Teaching Award for the College of Arts and Sciences in 1976. He now holds the title of Professor Emeritus. Teaching has always been an important part of his life. Contact with students invigorates him. He is the coauthor of two organic laboratory books that include techniques and experiments: INTRODUCTION TO ORGANIC LABORATORY TECHNIQUES: A MICROSCALE APPROACH (Cengage Learning), and A SMALL SCALE ARPPROACH TO ORGANIC LABORATORY TECHNIQUES (Cengage Learning), as well as MICROSCALE AND MACROSCALE TECHNIQUES IN THE ORGANIC LABORATORY (Cengage Learning), which highlights techniques to be used with a faculty member’s own experiments. He is a co-author, with Donald L. Pavia, George S. Kriz, and James R. Vyvyan of an organic spectroscopy book, INTRODUCTION TO SPECTROSCOPY, Fourth Edition (Cengage Learning). Professor Lampman also is the author of the computer program for teaching organic nomenclature: ORGANIC NOMENCLATURE: AN INTRODUCTION TO THE IUPAC SYSTEM. His research interests center on synthetic methods involving the reaction of free radicals on unsaturated cobaloximes (vitamin B12 model compounds), synthesis of strained small ring compounds, and chemical education. He is the author of 18 papers in these areas. He is a member of the American Chemical Society (Organic and Chemical Education divisions), and the Washington College Chemistry Teachers Association. George S. Kriz is Professor of Chemistry at Western Washington University. He earned his B.S. degree in chemistry from the University of California, and his Ph.D. from Indiana University, Bloomington, IN. In 1967 he joined the faculty at Western Washington University and recently served as department chair. He served as the General Chair of the 17th Biennial Conference on Chemical Education for 2001-2002. Professor Kriz was honored with the Peter J. Elich Excellence in Teaching Award (College of Arts and Sciences), Western Washington University, in 2000 and the Distinguised Service Award from the Division of Chemical Education, American Chemical Society (2010). He is the co-author with Donald Pavia, Gary Lampman, and Randall Engel of two organic laboratory books that include both techniques and experiments: INTRODUCTION TO ORGANIC LABORATORY TECHNIQUES: A MICROSCALE APPROACH (Cengage Learning), and A SMALL SCALE APPROACH TO ORGANIC LABORATORY TECHNIQUES (Cengage Learning). Their book, MICROSCALE AND MACROSCALE TECHNIQUES IN THE ORGANIC LABORATORY (Cengage Learning), includes techniques only, and can be used with a faculty member’s own experiments. He is a co-author, with Donald Pavia, Gary Lampman, and James Vyvyan, of an organic spectroscopy book, INTRODUCTION TO SPECTROSCOPY (Cengage Learning). Professor Kriz’s research interests include: developing new experiments for the organic chemistry laboratory; chemical education and the teaching of chemistry courses for general-understanding audiences; and determination of the structures of natural products using spectroscopic methods.
This book contains authoritative reviews regarding the field of Organometallic Chemistry, written by highly qualified experts within the area, and reviewed by other experts before publication. Because of this high standard, AOC is one of the most cited journals in both Organic and Inorganic Chemistry fields. * high quality of the articles* expertise of authors* careful editing that provides an easy-to-read material
About the Author
Pedro J. P rez (1965) graduated in Chemistry in 1987 in Sevilla. He received his Ph.D. degree in Chemistry (1991) at the Universidad de Sevilla, under the direction of Prof. Ernesto Carmona. As a Fulbright Scholar, he then joined Prof. Brookhart’s group at UNC-Chapel Hill (USA) where he started the research related to the use of copper-based catalysts for diazo decomposition. In 1994 he was invited research at DuPont Exptal station (Wilmington, Delaware). In 1993 he moved to a new University founded in Huelva, as an Assistant Professor (1993-1995), later becoming Lecturer (1995) and finally Professor of Inorganic Chemistry (2005). The general research interest of his group is related to the development of late transition-metal complexes for their use as catalysts in transformations with hydrocarbons. He is also responsible of the Homogeneous Catalysis Laboratory, an Associate Unit to the Spanish National Council of Research (CSIC), that is part of the Center for Research in Sustainable Chemistry at the Universidad de Huelva. He received the Inorganic Chemistry Award of the Royal Society of Chemistry of Spain (RSEQ) in 2007. From 2010 he is President of the Organometallic Division of the RSEQ and since 2011 he is also Secretary General of RSEQ. Currently he is also member of the Advisory Boards of Organometallics and European Journal of Inorganic Chemsitry.
Alkaloids – Secrets of Life: Alkaloid Chemistry, Biological Significance, Applications and Ecological Role, Second Edition provides knowledge on structural typology, biosynthesis and metabolism in relation to recent research work on alkaloids, considering an organic chemistry approach to alkaloids using biological and ecological explanation. The book approaches several questions and unresearched areas that persist in this field of research. It provides a beneficial text for academics, professionals or anyone who is interested in the fascinating subject of alkaloids. Each chapter features an abstract. Appendices, a listing of alkaloids, and plants containing alkaloids are all included, as are basic protocols of alkaloid analysis. * Presents the ecological role of alkaloids in nature and ecosystems interdisciplinary* Examines alkaloids from chemistry, biology and ecology viewpoints* A single handy reference volume comprehensively reviews the origin of alkaloids and their biological uses* Over 80% new information, including new chapters on the ecological role of alkaloids in nature and ecosystems and extraction of alkaloids
About the Author
Former (retired 2014) Professor in Applied Botany, University of Eastern Finland, Faculty of Science and Forestry, Department of Biology, Research and Teaching Laboratory of Applied Botany, Joensuu Campus. Internationally known, Chair of Phytochemical Section of the Botanical Society of America. Lifetime scientific title of docent in applied botany. Gold Medal for a Long Service to the Scientic Community.
An Introduction to Medicinal Chemistry is the leading text for university courses on this subject. Renowned for being a textbook loved equally by both students and lecturers, it presents complete coverage in an accessible and engaging style. The text begins with the essential biochemistry on which an understanding of medicinal chemistry is built, introducing the structure and function of important drug targets. It then explores how drugs interact with the body and the consequences of those reactions. There is a section on general principles and strategies involved in discovering and designing new drugs, and another on useful ‘tools of the trade’. The text ends with a contemporary look at specific topics within medicinal chemistry, for example, antiviral and anticancer agents; cholinergics and anticholinesterases; and antiulcer agents. Learning features throughout An Introduction to Medicinal Chemistry help to unlock this fascinating subject. A glossary helps to familiarise the language of medicinal chemistry. Boxes present in-depth material and explore how concepts are applied in practice. Key points summarise sections within chapters, providing a basis for revision, and questions at the end of chapters and on the accompanying Online Resource Centre allow the reader to test their understanding and develop molecular modelling skills. Online Resource Centre The Online Resource Centre features: For registered adopters of the book: * Answers to end-of-chapter questions * Figures from the book * Power Point slides * Test Bank questions For students: * Multiple Choice Questions * Web articles * Molecular Modelling Exercises * 3D Rotatable structures.
About the Author
Dr. Graham Patrick gained his BSc Honours at Glasgow University, winning the McKay-Smith Prize for Chemistry. He completed his PhD with Professor Kirby and Professor Robins studying the biosynthesis of gliotoxin and related fungal metabolites. Following this, he worked in the pharmaceutical industry as a research chemist and radiochemist on a variety of projects that included topic areas such as opioids, antibacterial agents and antidepressants. His academic career has included positions at Leeds and Strathclyde Universities as well as the Australian National University. He joined the University of Paisley (now the University of the West of Scotland) in 1990, teaching medicinal chemistry and drug design.
Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry with an emphasis on emerging topics in the biological sciences that are expected to provide the basis for entirely new future therapies. * Reviews on hot topics of interest in small molecule drug discovery heavily pursued by industrial research organizations* Provides preclinical information in the context of chemical structures* Knowledgeable section editors who evaluate invited reviews for scientific rigor
About the Author
Dr. Manoj Desai began his career in the pharmaceutical industry at Pfizer Inc, Central Research Division, Groton, CT (1986-1994) before moving to Chiron Corporation (1994-2003) as Director of medicinal chemistry; he was promoted to Vice President, lead discovery and medicinal chemistry (2000). In October 2003, he was appointed Vice President of medicinal chemistry at Gilead Sciences. At Pfizer, he was responsible for the medicinal chemistry efforts that lead to the discovery of oral Substance P antagonist CP-99994 which became the basis for the discovery of the new anti-emetics. At Chiron he formulated macrobead technology for the synthesis and screening of compound libraries for HTS and built the medicinal chemistry department with focus on kinase inhibitors. At Gilead, he was an active proponent to develop a pharmacoenhancer devoid of antiviral activity to improve the pharmacokinetics of integrase inhibitor elvitegravir. These efforts led to the discovery of Cobicistat which is one of components of StribildTM that was approved by FDA in August 2012 for the treatment of HIV infection. He is co-inventor on patents of Cobicistat (US 8,148,374), StribildTM and Ledipasvir (US 8,273,341; Phase III). Furthermore, his group at Gilead has advanced numerous compounds into clinical development for the treatment of antiviral diseases, cancer and cardiovascular diseases. Dr. Desai obtained Ph.D. in organic chemistry from the M.S. University of Baroda in 1981 working with Dr. Sukh Dev and then carried out post-doctoral fellowships at Purdue University working with Professor Herbert C. Brown (19981-1983) and at Harvard University with Professor Elias J. Corey (1983-1986). During his postdoctoral studies, he worked on natural product isolation, development of asymmetric synthetic methods using organoboranes and total synthesis of complex natural products such as retigeranic acid, ?-trans bergamotene and ginkgolide B. He has co-authored >60 publications in peer reviewed journals and is an inventor on >25 issued patents. Furthermore, Dr. Desai is Editor-in-Chief for Annual Reports in Medicinal chemistry (2012-current), and have co-edited Comprehensive Medicinal Chemistry II (volume 7). In 2013, he co-edited book titled “Successful Strategies for the Discovery of Antiviral Drugs .
This supplement can be used in any analytical chemistry course. The exercises teach students how to use Microsoft Excel using applications from statistics, data analysis equilibrium calculations, curve fitting, and more. Operations include everything from basic arithmetic and cell formatting to Solver, Goal Seek, and the Data Analysis Toolpak. The authors show students how to use a spreadsheet to construct log diagrams and to plot the results. Statistical data treatment includes descriptive statistics, linear regression, hypothesis testing, and analysis of variance. Tutorial exercises include nonlinear regression such as fitting the Van Deemter equation, fitting kinetics data, determining error coefficients in spectrophotometry, and calculating titration curves. Additional features include solving complex systems of equilibrium equations and advanced graphical methods: error bars, charts with insets, matrices and determinants, and much more.
About the Author
F. James Holler is a Professor of Chemistry and recipient of the Alumni Association Great Teacher Award at the University of Kentucky. He received his Ph.D. from Michigan State University. In addition to his role as co-author of several best-selling texts, he is co-creator of the world-famous Periodic Table of Comic Books.
Stanley R. Crouch is Professor Emeritus at Michigan State University. He received his undergraduate and M.S. degrees from Stanford University and his Ph.D. in analytical chemistry from the University of Illinois. He is the recipient of the 2001 American Chemical Society Division of Analytical Chemistry Award in Chemical Instrumentation and the 1996 ACS Division of Analytical Chemistry Award for Excellence in Teaching.
Atkins’ Physical Chemistry epitomises the benchmark of achievement for a chemistry degree throughout the world. Its broad coverage, concise explanations, and robust mathematical support are clearly presented in an engaging style to furnish students with a solid foundation in the subject. In this ninth edition the authors continue to refine their presentation of physical chemistry. The coverage of introductory topics is streamlined, and the addition of a new fundamentals chapter provides students with an overview of key principles on which the subject is based. The text includes increased coverage of computational chemistry and additional contextual examples of materials chemistry throughout, mirroring the current needs of today’s students and lecturers. Mathematics remains an intrinsic yet challenging part of physical chemistry. Extensive mathematical support, including a ‘Checklist of key equations’ at the end of every chapter, and ‘Mathematical background’ sections containing worked examples and self-tests, empower students to overcome any barriers to understanding that grasping the mathematical content might present. These features help to ensure the reader can master the subject without a need to sacrifice the rigour and depth of the mathematical content. The pedagogical framework, which is a hallmark of the authors’ writing, has been further strengthened. New ‘Key points’ provide summaries of the main take-home messages of each section and enable students to gain an overview of the topic before tackling it in depth; ‘Brief illustrations’ give a concise insight into how a particular mathematical concept is applied in practice, providing students with the opportunity to contextualise their learning. All these exciting new features and innovations are presented within a refreshed full colour text design, to stimulate and engage students yet further. The Online Resource Centre contains Living Graphs, illustrations from the book, and web links. An Instructor’s Solutions Manual (free to adopters) and a Student’s Solutions Manual are also available. Access to the Physical Chemistry eBook is also included with the purchase of the printed text. Offering enhanced functionality, including notetaking and highlighting, it also includes access to ‘Explorations in Physical Chemistry’, which contains interactive Excel worksheets and exercises related to the Living Graphs, allowing students to visualise, actively explore and test their understanding of the subject.
Thoroughly restructured and updated with new findings and new features The Second Edition of this internationally acclaimed text presents the latest developments in atmospheric science. It continues to be the premier text for both a rigorous and a complete treatment of the chemistry of the atmosphere, covering such pivotal topics as: Chemistry of the stratosphere and troposphere Formation, growth, dynamics, and properties of aerosols Meteorology of air pollution Transport, diffusion, and removal of species in the atmosphere Formation and chemistry of clouds Interaction of atmospheric chemistry and climate Radiative and climatic effects of gases and particles Formulation of mathematical chemical/transport models of the atmosphere All chapters develop results based on fundamental principles, enabling the reader to build a solid understanding of the science underlying atmospheric processes. Among the new material are three new chapters: Atmospheric Radiation and Photochemistry, General Circulation of the Atmosphere, and Global Cycles. In addition, the chapters Stratospheric Chemistry, Tropospheric Chemistry, and Organic Atmospheric Aerosols have been rewritten to reflect the latest findings. Readers familiar with the First Edition will discover a text with new structures and new features that greatly aid learning. Many examples are set off in the text to help readers work through the application of concepts. Advanced material has been moved to appendices. Finally, many new problems, coded by degree of difficulty, have been added. A solutions manual is available. Thoroughly updated and restructured, the Second Edition of Atmospheric Chemistry and Physics is an ideal textbook for upper-level undergraduate and graduate students, as well as a reference for researchers in environmental engineering, meteorology, chemistry, and the atmospheric sciences. Click here to Download the Solutions Manual for Academic Adopters: http://www.wiley.com/WileyCDA/Section/id-292291.html
About the Author
JOHN H. SEINFELD, PHD, is Louis E. Nohl Professor at the California Institute of Technology. Dr. Seinfeld is a member of the U.S. National Academy of Engineering and the American Academy of Arts and Sciences, and a Fellow of the American Association for the Advancement of Science, the American Institute of Chemical Engineers, and the American Geophysical Union. SPYROS N. PANDIS, PHD, is Professor of Chemical Engineering at the University of Patras, Greece, and EliasResearch Professor of Chemical Engineering and Engineering & Public Policy at Carnegie Mellon University.
The Eighth Edition of Zumdahl and DeCoste’s best-selling INTRODUCTORY CHEMISTRY: A FOUNDATION combines enhanced problem-solving structure with substantial pedagogy to enable students to become strong independent problem solvers in the introductory course and beyond. Capturing student interest through early coverage of chemical reactions, accessible explanations and visualizations, and an emphasis on everyday applications, the authors explain chemical concepts by starting with the basics, using symbols or diagrams, and conclude by encouraging students to test their own understanding of the solution. This step-by-step approach has already helped hundreds of thousands of students master chemical concepts and develop problem-solving skills. The book is known for its focus on conceptual learning and for the way it motivates students by connecting chemical principles to real-life experiences in chapter-opening discussions and “Chemistry in Focus” boxes.
About the Author
Steven S. Zumdahl is Professor Emeritus at the University of Illinois at Urbana-Champaign (UIUC), U.S.A, and has received numerous awards for his Chemistry teaching including: the National Catalyst Award for Excellence in Chemical Education and the School of Chemical Sciences Teaching award.
Donald J. DeCoste is Associate Director of General Chemistry at the University of Illinois, Urbana-Champaign and has been teaching chemistry at the high school and college levels for 26 years. He earned his BS in Chemistry and PhD from the University of Illinois, Urbana-Champaign. At UIUC he has developed chemistry courses for nonscience majors, preservice secondary teachers, and preservice elementary teachers. He teaches courses in introductory chemistry and the teaching of chemistry and has received the School of Chemical Sciences Teaching Award four times. Don has led workshops for secondary teachers and graduate student teaching assistants, discussing the methods and benefits of getting students more actively involved in class. When not involved in teaching and advising, Don enjoys spending time with his wife and three children.
The 9th edition of Malone’s Basic Concepts of Chemistry provides many new and advanced features that continue to address general chemistry topics with an emphasis on outcomes assessment.
New and advanced features include an objectives grid at the end of each chapter which ties the objectives to examples within the sections, assessment exercises at the end each section, and relevant chapter problems at the end of each chapter. Within Wiley PLUS, content is organized into “concept modules” that contain clear learning objectives from the text; examples, to help “show”how to do things; and automatically graded practice problems embedded in the content, to test knowledge.
A new Math Check allows quick access to the needed basic skill. The first chapter now includes brief introductions to several fundamental chemical concepts and Chapter Synthesis Problems have been added to the end of each chapter to bring key concepts into one encompassing problem. Every concept in the text is clearly illustrated with one or more step by step examples.Making it Real essays have been updated to present timely and engaging real-world applications, emphasizing the relevance of the material they are learning. This edition continues the end of chapter Student Workshop activities to cater to the many different learning styles and to engage users in the practical aspect of the material discussed in the chapter.
Focused, streamlined, and designed throughout to meet the needs of the one-term GOB Lab course, this manual features 14 easy-to-follow experiments (6 general chemistry, 4 organic chemistry, and 4 biochemistry) that include clear directions and illustrate the key concepts important for an allied health career. Pre- and post-lab questions for every experiment test the reader’s ability to apply concepts.
About the Author
Joseph M. Landesberg is a professor in the Department of Chemistry at Adelphi University. He came to Adelphi University in the fall of 1966. Prior to that, he was at Columbia University where he took a postdoctoral position with Professor Gilbert Stork. He received his Ph.D. from Harvard University where he wrote his thesis under the guidance of Professor Roy A. Olofson. Dr. Landesberg did his undergraduate work at Rutgers University.
This Cengage Technology Edition is the result of an innovative and collaborative development process. The textbook retains the hallmark approach of this respected text, whilst presenting the content in a print and digital hybrid that has been tailored to meet the rapidly developing demands of today’s lecturers and students. This blended solution offers a streamlined textbook for greater accessibility and convenience, complemented by a bolstered online presence, for a truly multi-faceted learning experience. Continuing Garrett and Grisham’s innovative conceptual and organizing ‘Essential Questions’ framework, Biochemistry, Cengage Technology Edition 5e, guides students through course concepts in a way that reveals the beauty and usefulness of biochemistry in the everyday world. Offering a balanced and streamlined presentation, this edition has been updated throughout with new material and revised presentations. For the first time, this book is integrated with OWL, a powerful online learning system for chemistry that engages students and improves learning outcomes.
About the Author
Reginald H. Garrett was educated in the Baltimore city public schools and at the Johns Hopkins University, where he received his Ph.D. in biology in 1968. Since that time, he has conducted research and taught biochemistry courses at the University of Virginia, where he is currently Professor of Biology. He is the author of numerous papers and review articles on biochemical, genetic, and molecular biological aspects of inorganic nitrogen metabolism. His early research focused on the pathway of nitrate assimilation in filamentous fungi. His investigations contributed substantially to our understanding of the enzymology, genetics, and regulation of this major pathway of biological nitrogen acquisition. More recently, he has collaborated in systems approaches to the metabolic basis of nutrition-related diseases. His research has been supported by grants from the National Institutes of Health, the National Science Foundation, and private industry. A member of the American Society for Biochemistry and Molecular Biology, Garrett is a former Fulbright Scholar, was twice Visiting Scholar at the University of Cambridge, and was Invited Professor at the University of Toulouse, France. Charles M. Grisham received his B.S. in chemistry from the Illinois Institute of Technology in 1969 and his Ph.D. in chemistry from the University of Minnesota in 1973. Following a postdoctoral appointment at the Institute for Cancer Research in Philadelphia, he became Professor of Chemistry at the University of Virginia, where he teaches biochemistry, introductory chemistry, and physical chemistry. He has authored numerous papers and review articles on active transport of sodium, potassium, and calcium in mammalian systems, on protein kinase C, and on the applications of NMR and EPR spectroscopy to the study of biological systems. His work has been supported by the National Institutes of Health, the National Science Foundation, the Muscular Dystrophy Association of America, the Research Corporation, the American Heart Association and the American Chemical Society. A member of the American Society for Biochemistry and Molecular Biology, Grisham held the Knapp Chair in Chemistry in 1999 at the University of San Diego; was Visiting Scientist at the Aarhus University Institute of Physiology, Aarhus, Denmark, for two years; and received a Research Career Development Award from the National Institutes of Health.
Succeed in the course with BIOCHEMISTRY. The authors’ innovative conceptual and organizing “Essential Questions” framework guides you through course concepts in a way that reveals the beauty and usefulness of biochemistry in the everyday world. Offering a balanced and streamlined presentation, this edition has been updated throughout with new material and revised presentations. This book is integrated with OWLv2, a powerful online learning system for chemistry with book-specific end-of-chapter material that will help you improve your grades and master course concepts.
About the Author
Charles M. Grisham received his B.S. in chemistry from the Illinois Institute of Technology in 1969 and his Ph.D. in chemistry from the University of Minnesota in 1973. Following a postdoctoral appointment at the Institute for Cancer Research in Philadelphia, he became Professor of Chemistry at the University of Virginia, where he teaches biochemistry, introductory chemistry, and physical chemistry. He has authored numerous papers and review articles on active transport of sodium, potassium, and calcium in mammalian systems, on protein kinase C, and on the applications of NMR and EPR spectroscopy to the study of biological systems. His work has been supported by the National Institutes of Health, the National Science Foundation, the Muscular Dystrophy Association of America, the Research Corporation, the American Heart Association and the American Chemical Society. A member of the American Society for Biochemistry and Molecular Biology, Grisham held the Knapp Chair in Chemistry in 1999 at the University of San Diego; was Visiting Scientist at the Aarhus University Institute of Physiology, Aarhus, Denmark, for two years; and received a Research Career Development Award from the National Institutes of Health. Reginald H. Garrett was educated in the Baltimore city public schools and at the Johns Hopkins University, where he received his Ph.D. in biology in 1968. Since that time, he has conducted research and taught biochemistry courses at the University of Virginia, where he is currently Professor of Biology. He is the author of numerous papers and review articles on biochemical, genetic, and molecular biological aspects of inorganic nitrogen metabolism. His early research focused on the pathway of nitrate assimilation in filamentous fungi. His investigations contributed substantially to our understanding of the enzymology, genetics, and regulation of this major pathway of biological nitrogen acquisition. More recently, he has collaborated in systems approaches to the metabolic basis of nutrition-related diseases. His research has been supported by grants from the National Institutes of Health, the National Science Foundation, and private industry. A member of the American Society for Biochemistry and Molecular Biology, Garrett is a former Fulbright Scholar, was twice Visiting Scholar at the University of Cambridge, and was Invited Professor at the University of Toulouse, France.
Ideal for those studying biochemistry for the first time, this proven book balances scientific detail with readability and shows you how principles of biochemistry affect your everyday life. Designed throughout to help you succeed (and excel!), the book includes in-text questions that help you master key concepts, end-of-chapter problem sets grouped by problem type that help you prepare for exams, and state-of-the art visuals that help you understand key processes and concepts. In addition, visually dynamic “Hot Topics” cover the latest advances in the field, while “Biochemical Connections” demonstrate how biochemistry affects other fields, such as health and sports medicine. The accompanying OWL homework offers end-of-chapter problems in digital form, giving you on-demand access to hints, solutions, and other information directly related to the problem.
About the Author
Owen M. McDougal is a professor of chemistry and biochemistry at Boise State University. A native of upstate New York, his love of the outdoors inspired him to travel west for graduate school and pursue a Ph.D. at the University of Utah in the laboratory of C. Dale Poulter. His work to elucidate the three-dimensional structures of neuropeptides by nuclear magnetic resonance spectroscopy involved the application of physical chemistry to address problems in biological systems. Upon completion of his Ph.D., Dr. McDougal sought an academic environment that allowed him to share his passion for science with students. He taught general, organic, and biological chemistry at Southern Oregon University which allowed him to hone his instructional skills. Looking to advance his love for writing, Owen shifted to a faculty position in the research-intensive environment at Boise State University, where he investigates the bioactivity of marine and terrestrial natural products, including studies of food chemistry, nutraceutical products, and specialty chemicals. Shawn O. Farrell, a native of Northern California, received his B.S. in biochemistry from University of California, Davis, studying carbohydrate metabolism. He completed his Ph.D. in biochemistry at Michigan State University, where he focused on the study of fatty acid metabolism. Dr. Farrell became interested in biochemistry while in college, as it was relevant to his passion for bicycle racing. He raced competitively for 15 years and now officiates bicycle races worldwide. He has taught biochemistry lecture and laboratory courses at Colorado State University for 16 years and now works for USCycling. Professor Farrell has written scientific journal articles about specific research projects and about laboratory teaching, as well as articles for sports publications, such as “Salmon, Trout, and Steelheader” magazine. He is co-author with Mary Campbell on BIOCHEMISTRY, 7e (Cengage Learning). Mary K. Campbell was Professor Emeritus of chemistry at Mount Holyoke College, where she taught biochemistry, general chemistry, and physical chemistry, as well as advised undergraduates working on biochemical research projects. Her avid interest in writing led to the publication of many highly successful editions of this textbook. Originally from Philadelphia, Dr. Campbell received her Ph.D. from Indiana University and completed postdoctoral work in biophysical chemistry at Johns Hopkins University. Her areas of interest included researching the physical chemistry of biomolecules, specifically, spectroscopic studies of protein-nucleic acid interactions. She was also coauthor with Shawn Farrell on BIOCHEMISTRY, 8th Edition (Cengage Learning), as well as several editions of GENERAL, ORGANIC, AND BIOCHEMISTRY by Bettelheim, Brown, Campbell, Farrell, and Torres.
The fourth edition of Biochemistry preserves the clear writing, strong physical chemistry background, and the use of the “Tools of Biochemistry” feature to underscore the experimental nature of biochemistry. This edition has been comprehensively and consistently updated to present the current developments in a rapidly evolving field.