Chemical Principles 8th Edition
Develop the qualitative, conceptual foundation you need to think like a chemist with CHEMICAL PRINCIPLES, 8e. Designed for students with solid mathematical preparation, this best-seller emphasizes models, everyday applications of chemistry, and a thoughtful, step-by-step problem-solving approach.
About the Author
Donald J. DeCoste is Associate Director of General Chemistry at the University of Illinois, Urbana-Champaign and has been teaching chemistry at the high school and college levels for 26 years. He earned his BS in Chemistry and PhD from the University of Illinois, Urbana-Champaign. At UIUC he has developed chemistry courses for nonscience majors, preservice secondary teachers, and preservice elementary teachers. He teaches courses in introductory chemistry and the teaching of chemistry and has received the School of Chemical Sciences Teaching Award four times. Don has led workshops for secondary teachers and graduate student teaching assistants, discussing the methods and benefits of getting students more actively involved in class. When not involved in teaching and advising, Don enjoys spending time with his wife and three children. Steve Zumdahl is the author of market-leading textbooks in introductory chemistry, general chemistry, honors-level chemistry, and high school chemistry. Recently retired from his long-time position as Director of Undergraduate Programs at the University of Illinois, he has received numerous awards for his contributions to chemical education. These include the National Catalyst Award in recognition of his contribution to chemical education, the University of Illinois Teaching Award, the UIUC Liberal Arts and Sciences Advising Award, and the School of Chemical Sciences Teaching Award (five times). He earned his B.S. in Chemistry from Wheaton College (IL), and his Ph.D. from the University of Illinois.
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Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry with an emphasis on emerging topics in the biological sciences that are expected to provide the basis for entirely new future therapies. * Reviews on hot topics of interest in small molecule drug discovery heavily pursued by industrial research organizations* Provides preclinical information in the context of chemical structures* Knowledgeable section editors who evaluate invited reviews for scientific rigor
About the Author
Dr. Manoj Desai began his career in the pharmaceutical industry at Pfizer Inc, Central Research Division, Groton, CT (1986-1994) before moving to Chiron Corporation (1994-2003) as Director of medicinal chemistry; he was promoted to Vice President, lead discovery and medicinal chemistry (2000). In October 2003, he was appointed Vice President of medicinal chemistry at Gilead Sciences. At Pfizer, he was responsible for the medicinal chemistry efforts that lead to the discovery of oral Substance P antagonist CP-99994 which became the basis for the discovery of the new anti-emetics. At Chiron he formulated macrobead technology for the synthesis and screening of compound libraries for HTS and built the medicinal chemistry department with focus on kinase inhibitors. At Gilead, he was an active proponent to develop a pharmacoenhancer devoid of antiviral activity to improve the pharmacokinetics of integrase inhibitor elvitegravir. These efforts led to the discovery of Cobicistat which is one of components of StribildTM that was approved by FDA in August 2012 for the treatment of HIV infection. He is co-inventor on patents of Cobicistat (US 8,148,374), StribildTM and Ledipasvir (US 8,273,341; Phase III). Furthermore, his group at Gilead has advanced numerous compounds into clinical development for the treatment of antiviral diseases, cancer and cardiovascular diseases. Dr. Desai obtained Ph.D. in organic chemistry from the M.S. University of Baroda in 1981 working with Dr. Sukh Dev and then carried out post-doctoral fellowships at Purdue University working with Professor Herbert C. Brown (19981-1983) and at Harvard University with Professor Elias J. Corey (1983-1986). During his postdoctoral studies, he worked on natural product isolation, development of asymmetric synthetic methods using organoboranes and total synthesis of complex natural products such as retigeranic acid, ?-trans bergamotene and ginkgolide B. He has co-authored >60 publications in peer reviewed journals and is an inventor on >25 issued patents. Furthermore, Dr. Desai is Editor-in-Chief for Annual Reports in Medicinal chemistry (2012-current), and have co-edited Comprehensive Medicinal Chemistry II (volume 7). In 2013, he co-edited book titled “Successful Strategies for the Discovery of Antiviral Drugs .
Providing an excellent compilation of the most important and useful methods of modern stereoselective synthesis, this book features illustrative examples of drug and natural product syntheses, resulting in a rich source of stimulating ideas for the efficient use of asymmetric reactions in the users’ own synthesis. The authors adopt a novel approach in not attempting to present this rapidly developing area in its entirety, but to distill the truly groundbreaking reactions that should be in the repertoire of every synthetic organic chemist.
About the Author
Erick M. Carreira, born in La Habana, Cuba, obtained a B.S. degree in 1984 from the University of Illinois at Urbana Champaign under the supervision of Scott E. Denmark, and a PhD in 1990 from Harvard University under the supervision of David A. Evans. After carrying out postdoctoral work with Peter Dervan at the California Institute of Technology through mid-1992, he joined the faculty at the same institution as an assistant professor of chemistry and was promoted to full professor in 1997. In 1998, he moved to the Laboratory of Organic Chemistry at the ETH-Zurich, Switzerland. He has over 180 research publications and numerous patents to his name. He is the recipient of, among others, the American Chemical Society Award in Pure Chemistry the Nobel Laureate Signature Award, and he has held the David and Lucile Packard Foundation Fellowship in Science and Engineering as well as the Tetrahedron Chair Prize. Professor Carreira’s research program is focused on the four interrelated areas of organic synthesis: catalysis, methodology, natural products synthesis, and bioorganic chemistry. Lisbet Kvaerno, born in Denmark, received her M.Sc. in chemistry from the University of Copenhagen under Prof. Jesper Wengel. She obtained her PhD in 2004 after working in total synthesis at the Technical University of Denmark under Prof. David Tanner and in medicinal chemistry at the ETH Zurich supervised by Prof. Erick M. Carreira. As a postdoctoral fellow in the research group of Prof. David A. Evans at Harvard University, she completed the total synthesis of the marine natural product ( )-azaspiracid. After a brief period as an independent junior group leader at the Max Planck Institute of Coal Research in Muelheim, Germany, she joined Lundbeck in Copenhagen as a process chemist in the late summer of 2008.
Please note that the digital access code that comes with the print book is valid for use in a specific Asia territory only.
CB CourseSmart eBook – The ultimate eBook experience has arrived! Easily access our eBooks with features that will improve your reading experience, and tools to help you take notes and organize your studies.
Succeed in the course with this student-friendly, proven text. Designed throughout to help you master key concepts and improve your problem-solving skills, CHEMISTRY, Seventh Edition includes a running margin glossary, end-of-chapter in-text mini study guides, a focus on “how to” skills, and more in-chapter examples and problems than any text on the market. To help you understand reaction mechanisms, the authors offset them in a stepwise fashion and emphasize similarities between related mechanisms using just four different characteristics: breaking a bond, making a new bond, adding a proton, and taking a proton away. Thoroughly updated throughout, the book offers numerous biological examples for premed students, unique roadmap problems, a wide range of in-text learning tools, and integration with an online homework and tutorial system, which now includes an interactive multimedia eBook.
About the Author
William H. Brown
William H. Brown is emeritus professor of chemistry at Beloit College, where he was twice named Teacher of the Year. His teaching responsibilities include organic chemistry, advanced organic chemistry, and, more recently, special topics in pharmacology and drug synthesis. He received his Ph.D. from Columbia University under the direction of Gilbert Stork and did postdoctoral work at California Institute of Technology and the University of Arizona. He is a coauthor on ORGANIC CHEMISTRY, 10e (Cengage Learning).
Brent L. Iverson
Brent L. Iverson received his Ph.D. from Stanford University in 1982 and currently teaches at University of Texas, Austin. He is a distinguished teacher and respected researcher. Iverson’s research group has developed methods for recombinant antibody or enzyme cloning and has directed its evolution. In collaboration with the Georgiou group, he pioneered a novel E. coli surface expression/FACS selection technology that has allowed the group to enhance antibody affinity.
Eric Anslyn is the Norman Hackerman Professor of Chemistry at The University of Texas at Austin. Highly respected in organic chemistry, he earned his Ph.D. from the California Institute of Technology and has won numerous teaching awards. Anslyn’s research focuses on the cutting-edge area of bioorganic chemistry.
Christopher S. Foote
Christopher S. Foote received his B.S. in 1957 from Yale University and his Ph.D. in 1962 from Harvard University. His scholarly credits include Sloan Fellow 1965-1967; Guggenheim Fellow 1967-1968; ACS Baekland Award, 1975; ACS Cope Scholar, 1994; Southern California Section ACS Tolman Medal, 1996; President, American Society for Photobiology, 1988-1989; and Senior Editor, ACCOUNTS OF CHEMICAL RESEARCH. He was Professor of Chemistry at UCLA.
This book contains authoritative reviews regarding the field of Organometallic Chemistry, written by highly qualified experts within the area, and reviewed by other experts before publication. Because of this high standard, AOC is one of the most cited journals in both Organic and Inorganic Chemistry fields. * high quality of the articles* expertise of authors* careful editing that provides an easy-to-read material
About the Author
Pedro J. P rez (1965) graduated in Chemistry in 1987 in Sevilla. He received his Ph.D. degree in Chemistry (1991) at the Universidad de Sevilla, under the direction of Prof. Ernesto Carmona. As a Fulbright Scholar, he then joined Prof. Brookhart’s group at UNC-Chapel Hill (USA) where he started the research related to the use of copper-based catalysts for diazo decomposition. In 1994 he was invited research at DuPont Exptal station (Wilmington, Delaware). In 1993 he moved to a new University founded in Huelva, as an Assistant Professor (1993-1995), later becoming Lecturer (1995) and finally Professor of Inorganic Chemistry (2005). The general research interest of his group is related to the development of late transition-metal complexes for their use as catalysts in transformations with hydrocarbons. He is also responsible of the Homogeneous Catalysis Laboratory, an Associate Unit to the Spanish National Council of Research (CSIC), that is part of the Center for Research in Sustainable Chemistry at the Universidad de Huelva. He received the Inorganic Chemistry Award of the Royal Society of Chemistry of Spain (RSEQ) in 2007. From 2010 he is President of the Organometallic Division of the RSEQ and since 2011 he is also Secretary General of RSEQ. Currently he is also member of the Advisory Boards of Organometallics and European Journal of Inorganic Chemsitry.