Organic Chemistry 5th Edition
Written by two expert teachers, the Fifth Edition of Organic Chemistry is written to support all kinds of learners whether students read the book, or use it as a reference. New Visualize, Understand, Draw sections help students draw molecules well, visualize how they are formed, and understand why reactions occur. The Fifth Edition has been revised to be more accessible, with a focus on the basics and more opportunities for problem-solving practice, while the robust media package helps students visualize organic chemistry.
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Annual Reports in Medicinal Chemistry provides timely and critical reviews of important topics in medicinal chemistry with an emphasis on emerging topics in the biological sciences that are expected to provide the basis for entirely new future therapies. * Reviews on hot topics of interest in small molecule drug discovery heavily pursued by industrial research organizations* Provides preclinical information in the context of chemical structures* Knowledgeable section editors who evaluate invited reviews for scientific rigor
About the Author
Dr. Manoj Desai began his career in the pharmaceutical industry at Pfizer Inc, Central Research Division, Groton, CT (1986-1994) before moving to Chiron Corporation (1994-2003) as Director of medicinal chemistry; he was promoted to Vice President, lead discovery and medicinal chemistry (2000). In October 2003, he was appointed Vice President of medicinal chemistry at Gilead Sciences. At Pfizer, he was responsible for the medicinal chemistry efforts that lead to the discovery of oral Substance P antagonist CP-99994 which became the basis for the discovery of the new anti-emetics. At Chiron he formulated macrobead technology for the synthesis and screening of compound libraries for HTS and built the medicinal chemistry department with focus on kinase inhibitors. At Gilead, he was an active proponent to develop a pharmacoenhancer devoid of antiviral activity to improve the pharmacokinetics of integrase inhibitor elvitegravir. These efforts led to the discovery of Cobicistat which is one of components of StribildTM that was approved by FDA in August 2012 for the treatment of HIV infection. He is co-inventor on patents of Cobicistat (US 8,148,374), StribildTM and Ledipasvir (US 8,273,341; Phase III). Furthermore, his group at Gilead has advanced numerous compounds into clinical development for the treatment of antiviral diseases, cancer and cardiovascular diseases. Dr. Desai obtained Ph.D. in organic chemistry from the M.S. University of Baroda in 1981 working with Dr. Sukh Dev and then carried out post-doctoral fellowships at Purdue University working with Professor Herbert C. Brown (19981-1983) and at Harvard University with Professor Elias J. Corey (1983-1986). During his postdoctoral studies, he worked on natural product isolation, development of asymmetric synthetic methods using organoboranes and total synthesis of complex natural products such as retigeranic acid, ?-trans bergamotene and ginkgolide B. He has co-authored >60 publications in peer reviewed journals and is an inventor on >25 issued patents. Furthermore, Dr. Desai is Editor-in-Chief for Annual Reports in Medicinal chemistry (2012-current), and have co-edited Comprehensive Medicinal Chemistry II (volume 7). In 2013, he co-edited book titled “Successful Strategies for the Discovery of Antiviral Drugs .
Principles of Physical Chemistry, Second Edition uniquely uses simple physical models as well as rigorous treatments for understanding molecular and supramolecular systems and processes. In this way the presentation assists students in developing an intuitive understanding of the subjects as well as skill in quantitative manipulations. The unifying nature of physical chemistry is emphasized in the book by its organization – beginning with atoms and molecules, and proceeding to molecular assemblies of increasing complexity, ending with the emergence of matter that carries information, i.e. the origin of life, a physicochemical process of unique importance. The aim is to show the broad scope and coherence of physical chemistry.
International Review of Cell and Molecular Biology presents comprehensive reviews and current advances in cell and molecular biology. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. The series has a world-wide readership, maintaining a high standard by publishing invited articles on important and timely topics authored by prominent cell and molecular biologists. * Authored by some of the foremost scientists in the field * Provides comprehensive reviews and current advances* Wide range of perspectives on specific subjects* Valuable reference material for advanced undergraduates, graduate students and professional scientists
About the Author
Kwang Jeon received his Ph.D. in cell physiology at King’s College, University of London, UK, in 1964 and taught at SUNY Buffalo and University of Tennessee. His research was concerned with the biogenesis and function of cell components in two major areas: Integration of intracellular symbionts into host cells leading to the acquisition of new cell components and cell variation; Membrane-protein recycling during endo- and exocytosis.
Laboratory Manual for General, Organic, and Biological Chemistry can accompany the lab portion of any one-semester GOB chemistry course. Most experiments include a link to the health sciences, such as nursing and nutrition, while concepts are framed in real-world questions and are broadly applicable. Many of the experiments illustrate concepts from more than one chapter of the text and often utilize basics from the areas of general, organic, or biological chemistry to develop concepts in one or more of the other areas. This integrated strategy helps students to understand that chemistry is not a disparate set of unrelated concepts. Using this integrated approach, students develop the skills to help them understand chemistry and to see its applications in their everyday lives.
About the Author
Todd S. Deal received his B.S. degree in chemistry in 1986 from Georgia Southern College (now University) in Statesboro, Georgia, and his Ph.D. in chemistry in 1990 from The Ohio State University. He joined the faculty of his undergraduate alma mater in 1992, where he currently serves as Director of the Office of Student Leadership and Civic Engagement. Professor Deal has taught chemistry to allied health and preprofessional students for 20 years. In 1994, he was selected Professor of the Year by the students at Georgia Southern University. Professor Deal is also the recipient of the Allen E. Paulson College of Science and Technology’s Award for Excellence in Teaching (2003), the Georgia Southern University Award for Excellence in Contributions to Instruction (2003), and the Allen E. Paulson College of Science and Technology’s Award for Excellence in Service (2006).